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APOB Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against full-length native APOB.

Manufacturer:  Abnova Corporation PAB1279

Catalog No. 89-116-093


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Description

Description

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq

Specifications

Specifications

APOB
Unconjugated
Western Blot (1:10000-1:80000) ELISA (1:10000-1:80000) The optimal working dilution should be determined by the end user.
APOB
FLDB
Goat
1 mg
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
This antibody specifically binds to human APOB.
ELISA, Western Blot
Goat polyclonal antibody raised against full length native APOB.
In 75mM PBS, 75mM NaCl, 0.5mM EDTA, pH 7.2 (0.02% sodium azide)
Liquid
APOB
Native purified human APOB.
RUO
Primary
338
Human
SDS
Documents
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