APOE, Goat, Biotin, Polyclonal Antibody, Abnova
Goat polyclonal antibody raised against native APOE.
Manufacturer: Abnova Corporation PAB14368
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
|ELISA (1:100-1:10000) Western Blot (1:100-1:10000) The optimal working dilution should be determined by the end user.|
|Store at -20°C on dry atmosphere. After reconstitution with 500μL deionized water|
|This antibody can be used for detection of APOE in human plasma and lipoproteins.|
|ELISA, Western Blot|
|Goat polyclonal antibody raised against native APOE.|
|Lyophilized from 75mM PBS, 75mM NaCl, 0.02% sodium azide, 0.5mM EDTA, pH 7.2.|
|Native purified human APOE.|
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For Research Use Only