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APOE, Goat, Biotin, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against native APOE.

Manufacturer:  Abnova Corporation PAB14368

Catalog No. 89-117-020


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Description

Description

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Specifications

Specifications

APOE
Biotin
ELISA (1:100-1:10000) Western Blot (1:100-1:10000) The optimal working dilution should be determined by the end user.
APOE
AD2|LPG|MGC1571|apoprotein
Goat
500 uL
Store at -20°C on dry atmosphere. After reconstitution with 500μL deionized water
Polyclonal
This antibody can be used for detection of APOE in human plasma and lipoproteins.
ELISA, Western Blot
Goat polyclonal antibody raised against native APOE.
Lyophilized from 75mM PBS, 75mM NaCl, 0.02% sodium azide, 0.5mM EDTA, pH 7.2.
Lyophilized
APOE
Native purified human APOE.
RUO
Primary
348
Human
SDS
Documents
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