CACNB4 Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of CACNB4.

Supplier:  Abnova Corporation PAB6720

Catalog No. 89-132-629

Description

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: CSPGGYSHDSRHRL

Specifications

• Antigen: CACNB4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:8000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: CACNB4
• Gene Alias: CAB4/CACNLB4/EA5/EJM
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 785
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of CACNB4.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_001005747.1;NP_000717.2;NP_001005746.1
• Gene Symbols: CACNB4
• Immunogen: A synthetic peptide corresponding to human CACNB4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize all reported protein isoforms of human CACNB4 (NP_001005747.1, NP_000717.2, NP_001005746.1, ).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only