PRDM16, Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of PRDM16.
Supplier: Abnova Corporation PAB6224
The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeqSequence: C-TSESGAFHPINHL
|ELISA (1:32000) The optimal working dilution should be determined by the end user.
|A synthetic peptide corresponding to human PRDM16.
|Goat polyclonal antibody raised against synthetic peptide of PRDM16.
|In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
|Antigen affinity purification
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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