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PSMB10, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of PSMB10.

Manufacturer:  Abnova Corporation PAB14399

Catalog No. 89-117-041


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Description

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq

Sequence: C-PTEPVKRSGRYH
Specifications

Specifications

PSMB10
0.5 mg/mL
Goat polyclonal antibody raised against synthetic peptide of PSMB10.
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Liquid
PSMB10
A synthetic peptide corresponding to human PSMB10.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Approx 26 KDa band observed in human, liver, lung and lymph node lysates (calculated MW of 28.9 KDa according to NP_002792.1).
ELISA, Western Blot
Unconjugated
ELISA (1:8000) Western Blot (0.3-1 ug/mL).) The optimal working dilution should be determined by the end user.
PSMB10
LMP10|MECL1|MGC1665|beta2i
Goat
Antigen affinity purification
RUO
Primary
5699
Human
SDS
Documents
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