PSMB10, Goat, Polyclonal Antibody, Abnova
Goat polyclonal antibody raised against synthetic peptide of PSMB10.
Manufacturer: Abnova Corporation PAB14399
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeqSequence: C-PTEPVKRSGRYH
|Goat polyclonal antibody raised against synthetic peptide of PSMB10.|
|In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)|
|A synthetic peptide corresponding to human PSMB10.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Approx 26 KDa band observed in human, liver, lung and lymph node lysates (calculated MW of 28.9 KDa according to NP_002792.1).|
|ELISA, Western Blot|
|ELISA (1:8000) Western Blot (0.3-1 ug/mL).) The optimal working dilution should be determined by the end user.|
|Antigen affinity purification|
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