THRB, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of THRB.

Supplier:  Abnova Corporation PAB7340

Catalog No. 89-133-163

Description

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq

Sequence: C-REELQKSIGHKP

Specifications

• Antigen: THRB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:32000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: THRB
• Gene Symbols: THRB
• Immunogen: A synthetic peptide corresponding to human THRB.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is not expected to cross-react to THRA.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of THRB.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: ERBA-BETA/ERBA2/GRTH/MGC126109/MGC126110/NR1A2/PRTH/THR1/THRB1/THRB2
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7068
• Target Species: Human
• Form: Liquid

For Research Use Only