Invitrogen™ GPR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532787

Catalog No. PIPA532787

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Bat, Elephant, Pig (94%); Dog, Horse, Platypus (88%); Panda (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR1 is an orphan receptor for the inflammation-associated leukocyte chemoattractant chemerin, suggesting a role for this receptor in the regulation of inflammation. In yeast, G protein-coupled receptor 1 senses glucose and controls filamentous growth. It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism.

Specifications

• Antigen: GPR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR1
• Gene Alias: Chemerin receptor 2; CMKLR2; G protein-coupled receptor 1; GPR1; Gpr-1; G-protein coupled receptor 1; probable G-protein coupled receptor 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2825
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P46091
• Gene Symbols: GPR1
• Immunogen: Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human GPR1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov