GPR109B Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141622

Catalog No. 01-675-238

Description

PA1-41622 detects GPR109B in chimpanzee and human samples. This antibody is predicted to react with canine and hamster based on sequence homology.

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. [UniProt]

Specifications

• Antigen: GPR109B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HCAR3
• Gene Alias: G protein-coupled receptor 109B; GPR109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GTP-binding protein; HCA3; HCAR3; HM74; HM74B; hydroxycarboxylic acid receptor 3; hydroxy-carboxylic acid receptor 3; Niacin receptor 2; NIACR2; Nicotinic acid receptor 2; PUMAG; Puma-g; putative chemokine receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8843
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: P49019
• Gene Symbols: HCAR3
• Immunogen: Synthetic peptide corresponding to residues 1-50 of human GPR109B.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Non-human Primate
• Product Type: Antibody
• Isotype: IgG