Invitrogen™ GPR17 Monoclonal Antibody (OTI17C1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527501

Catalog No. PIMA527501

Description

GPR17 Monoclonal Antibody for IHC (P)

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.

Specifications

• Antigen: GPR17
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13304
• Gene Symbols: GPR17
• Immunogen: Synthetic peptide within Human GPR17 C-terminal.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin)
• Clone: OTI17C1
• Conjugate: Unconjugated
• Gene: GPR17
• Gene Alias: AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2840
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid