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GPR17 Mouse anti-Human, Clone: OTI9D6, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA811834

Encompass_Preferred

Catalog No. 50-168-4278


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Description

Description

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
Specifications

Specifications

GPR17
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q13304
GPR17
Synthetic peptide
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin)
OTI9D6
Unconjugated
GPR17
G protein-coupled receptor 17
Mouse
Affinity Chromatography
RUO
2840
-20° C, Avoid Freeze/Thaw Cycles
Liquid
SDS
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