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GPR56 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550979

Catalog No. PA550979


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Description

Description

GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.

Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintece of the pial basement membrane integrity and in cortical lamination (PubMed:21768377). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Plays a role in the maintece of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (PubMed:23478665). Plays a critical role in tumourigenesis. Plays essential role in testis development (PubMed:20981830). {ECO:0000250; UniProtKB:Q9Y653, ECO:0000269; PubMed:18378689, ECO:0000269; PubMed:18509043, ECO:0000269; PubMed:19515912, ECO:0000269; PubMed:20981830, ECO:0000269; PubMed:21768377, ECO:0000269; PubMed:23478665, ECO:0000269; PubMed:24531968}.
Specifications

Specifications

GPR56
Polyclonal
Unconjugated
ADGRG1
Liquid
ADGRG1
Synthesized peptide derived from the Internal region of human GPR56.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q9Y653
BFPP, DKFZp781L1398, TM7LN4, TM7XN1
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9289
Documents
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