Invitrogen™ GPR56 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533740

Catalog No. PIPA533740

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee (100%) Gorilla, Orangutan, Gibbon, Marmoset (94%) Monkey (89%) Panda, Bovine (83%).

GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: GPR56
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRG1
• Gene Alias: 7-transmembrane protein with no EGF-like N-terminal domains-1; Adgrg1; ADGRG1 CT; ADGRG1 C-terminal fragment; ADGRG1 NT; ADGRG1 N-terminal fragment; ADGRG1-CT; adhesion G protein-coupled receptor G1; adhesion G-protein coupled receptor G1; BFPP; BPPR; Cyt28; DKFZp781L1398; G protein-coupled receptor 56; Gpr56; GPR56 7TM; GPR56 CT; GPR56 C-terminal fragment; GPR56 extracellular subunit; GPR56 NT; GPR56 N-terminal fragment; GPR56 seven-transmembrane subunit; GPR56 subunit alpha; GPR56 subunit beta; G-protein coupled receptor 56; Protein TM7XN1; secretin receptor; serpentine receptor cyt28; testicular tissue protein Li 77; TM7LN4; TM7XN1; UNQ540/PRO1083
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9289
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9Y653
• Gene Symbols: ADGRG1
• Immunogen: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPR56.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG