Invitrogen™ GPR83 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533770

Catalog No. PIPA533770

Description

Percent identity with other species by BLAST analysis: Human (93%) Chimpanzee, Gorilla, Orangutan, Monkey, Mouse (87%) Gibbon, Galago, Marmoset, Rat, Bat, Hamster, Rabbit, Horse (80%).

GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.

Specifications

• Antigen: GPR83
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR83
• Gene Alias: AW045253; G protein-coupled receptor 72; G protein-coupled receptor 83; Gir; glucocorticoid induced receptor; glucocorticoid-induced receptor; GPR72; Gpr83; G-protein coupled receptor 72; Hcepto9; Jp05; KIAA1540; Probable G-protein coupled receptor 83; RP105; RP39; RP82
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10888
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9NYM4
• Gene Symbols: GPR83
• Immunogen: Synthetic 16 amino acid peptide from C-terminus of human GPR83.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG