BioVision Inc Granzyme B Activity Fluorometric Assay Kit: Granzyme B Activity Assay Kit: Fluorometric Assay to Measure Granzyme B Activity & Characterize/Study Granzyme B Inhibitors. Rapid, Simple & Sensitive. 100 Assays.
Manufacturer: BioVision Inc K168100
Granzyme B (GZMB, EC number 184.108.40.206) also known as Granzyme-2 is a serine protease stored in the granules of activated cytotoxic T cells and NK cells. Upon target cell contact, Granzyme B is directionally exocytosed and with the assistance of perforin enters the target cell. With its unique substrate specificity (Granzyme B prefers an aspartic acid residue at the P1 site of its substrates), Granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell. In BioVision’s Granzyme B Activity Assay Kit, active human Granzyme B enzyme hydrolyzes the specific substrate to release the quench of fluorescent group, which can be detected fluorometrically at Ex/Em = 380/500 nm. This Assay Kit is rapid, reliable and sensitive and can detect Granzyme B activity in various biological samples. BioVision charges an Ice pack and Insulated Container fee of $25.00 for each order.
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