GRASP1 Mouse anti-Human, Clone: OTI1E3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525035
DescriptionPDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|GRASP-1, GRIP-1, GRIP1, GRIPAP1, KIAA1167, GRIP1-associated protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of GRIPAP1 produced in HEK293T cell|
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