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GRASP1 Mouse anti-Human, Clone: OTI2C11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525032

Catalog No. PIMA525032


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Description

Description

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
Specifications

Specifications

GRASP1
Monoclonal
0.5 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q4V328
GRASP-1, GRIP-1, GRIP1, GRIPAP1, KIAA1167, GRIP1-associated protein 1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
56850
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI2C11
Unconjugated
GRIPAP1
Liquid
GRIPAP1
Full length human recombit protein of GRIPAP1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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