Invitrogen™ GRB14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528914

Catalog No. PIPA528914

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver. Predicted reactivity: Mouse (88%), Rat (86%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.

Specifications

• Antigen: GRB14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRB14
• Gene Alias: AI505286; GRB14; GRB14 adapter protein; growth factor receptor bound protein 14; growth factor receptor-bound protein 14
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2888, 50915
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.52 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300
• Gene Accession No.: Q14449, Q9JLM9
• Gene Symbols: GRB14
• Immunogen: Recombinant fragment corresponding to a region within amino acids 24 and 391 of Human GRB14.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG