GRIA4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 233501AP
DescriptionGlutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P19493, P48058, Q9Z2W8|
|GluA4, GluR 4, GluR D, GLUR4, GLUR4C, GLURD, Glutamate receptor 4, GRIA4|
|14802, 2893, 29629|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|GRIA4 Fusion Protein Ag19949|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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