Invitrogen™ GSDMB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554929

Catalog No. PIPA554929

Description

Immunogen sequence: AGGDMIAVRS LVDADRFRCF HLVGEKRTFF GCRHYTTGLT LMDILDTDGD KWLDELDSGL QGQKAEFQIL DNVDSTGELI VRLPKEIT Highest antigen sequence identity to the following orthologs: Mouse - 34%, Rat - 33%.

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Specifications

• Antigen: GSDMB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GSDMB
• Gene Alias: gasdermin B; gasdermin-B; Gasdermin-like protein; GSDMB; GSDML; PP4052; PRO2521
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55876
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TAX9
• Gene Symbols: GSDMB
• Immunogen: Recombinant protein corresponding to Human GSDMB. Recombinant protein control fragment (Product #RP-93176).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov