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Tocris™ GSK 2194069

Potent human fatty acid synthase (hFASN) inhibitor

Manufacturer:  Tocris™ 5303/10

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Catalog No. 53-031-0

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For Research Use Only



Potent human fatty acid synthase (hFASN) inhibitor (IC50 = 7.7nM); inhibits hFAS β-ketoacyl reductase activity. Inhibits lipid synthesis and attenuates proliferation of A549 non-small-cell lung cancer cells (EC50 = 15nM) in vitro.
  • Chemical Name: 4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
  • Formula: C25H24N4O3
  • CAS Number: 1332331-08-4
  • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
  • Purity: >99
Description & Specifications


GSK 2194069
GSK 2194069
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