Tocris™ GSK 4112

Selective Rev-Erbalpha agonist

Manufacturer: Tocris™ 3663/50

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Catalog No. 36-635-0R

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Disclaimers:

For Research Use Only


    Specifications

    Product Type GSK 4112
    Inhibitors GSK 4112
    Purity >98
    Molecular Weight 396.89
    Quantity 50mg

    Selective Rev-Erbα agonist (EC50 = 250nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erbα; causes acute suppression of Bmal1 gene transcription. Induces phase shifts in the circadian clock.

    • Chemical Name: 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate
    • Formula: C18H21ClN2O4S
    • CAS Number: 1216744-19-2
    • Solubility: Soluble to 25mM in DMSO
    • Purity: >98

  • Description & Specifications

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