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GSK2578215A, Tocris Bioscience™

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Quantity:
10mg
This item is not returnable. View return policy
1285515-21-0
C24H18FN3O2
399.425
WCIGMFCFPXZRMQ-UHFFFAOYSA-N
unii-q641jsf42x,2-benzyloxy-5-2-fluoropyridin-4-yl-n-pyridin-3-yl benzamide,lrrk2-kinase inhibitor,benzamide, 5-2-fluoro-4-pyridinyl-2-phenylmethoxy-n-3-pyridinyl,5-2-fluoro-4-pyridinyl-2-phenylmethoxy-n-3-pyridinylbenzamide,5-2-fluoropyridin-4-yl-2-phenylmethoxy-n-pyridin-3-ylbenzamide,5-2-fluoro-4-pyridinyl-2-phenylmethyl oxy-n-3-pyridinylbenzamide
68107965
5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4
This item is not returnable. View return policy
1285515-21-0
C24H18FN3O2
399.425
WCIGMFCFPXZRMQ-UHFFFAOYSA-N
unii-q641jsf42x,2-benzyloxy-5-2-fluoropyridin-4-yl-n-pyridin-3-yl benzamide,lrrk2-kinase inhibitor,benzamide, 5-2-fluoro-4-pyridinyl-2-phenylmethoxy-n-3-pyridinyl,5-2-fluoro-4-pyridinyl-2-phenylmethoxy-n-3-pyridinylbenzamide,5-2-fluoropyridin-4-yl-2-phenylmethoxy-n-pyridin-3-ylbenzamide,5-2-fluoro-4-pyridinyl-2-phenylmethyl oxy-n-3-pyridinylbenzamide
68107965
5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4

Potent, selective LRRK2 inhibitor; brain penetrant

Potent, selective LRRK2 inhibitor; brain penetrant

Potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
Quantity 10mg
Formula Weight 399.42
Percent Purity >99%
Chemical Name or Material GSK2578215A

Recommended Storage : Store at Room Temperature