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GSK2578215A, Tocris Bioscience™

Potent, selective LRRK2 inhibitor; brain penetrant

Manufacturer:  Tocris Bioscience 4629/5

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Catalog No. 46-295


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Description

Description

Potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
Specifications

Specifications

5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide
>99%
Observed MW: 399.42
1285515-21-0
C24H18FN3O2
5mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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