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GSTA3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 167031AP

Catalog No. 50-173-1127


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Description

Description

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Specifications

Specifications

GSTA3
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P04904, P30115, Q16772
Glutathione S transferase A3, Glutathione S transferase A3 3, GST class alpha member 3, GSTA3, GSTA3 3, GTA3
Rabbit
IgG
150 μL
-20°C
Primary
14859, 2940, 494500
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
GSTA3
Liquid
Gsta3
GSTA3 Fusion Protein Ag10101
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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