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GSTM4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 167661AP

Catalog No. 50-173-1165


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Description

Description

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual ft.s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.
Specifications

Specifications

GSTM4
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q03013
glutathione S transferase mu 4, GST class mu 4, GST Mu2, GSTM4, GSTM4 4, GTM4
Rabbit
IgG
150 μL
-20°C
Primary
14865, 2948, 499689
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
GSTM4
Liquid
Gstm4
GSTM4 Fusion Protein Ag10340
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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