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GTF2E1 Mouse anti-Human, Clone: 1E12, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524398

Catalog No. PIMA524398


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Description

Description

Peptide Sequence: SCVKEEDMLE LLKFDRKQLR SVLNNLKGDK FIKCRMRVET AADGKTTRHN YYFINYRTLV NVVKYKLDHM RRRIETDERD STNRASFKCP VCSSTFTDLE

The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57, 000 (TFIIE-alpha) and 34, 000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombit TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation.
Specifications

Specifications

GTF2E1
Monoclonal
Unconjugated
GTF2E1
Liquid
GTF2E1
GTF2E1 (NP_005504, 41 a.a. ∽ 140 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
200 μL
-20° C
Primary
2960
ELISA, Western Blot
1E12
ascites with no preservative
P29083
General transcription factor IIE subunit 1, General transcription factor IIE 56 kDa subunit, Transcription initiation factor IIE subunit alpha, TFIIE-alpha, GTF2E1, TF2E1
Mouse
IgM, kappa
RUO
Antibody
Monoclonal
Human
Documents
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