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GTF2F1 Mouse anti-Canine, Human, Non-human primate, Clone: OTI4B10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525696

Catalog No. PIMA525696

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In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.


0.44 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
BTF4; C76800; General transcription factor IIF 74 kDa subunit; General transcription factor IIF subunit 1; General transcription factor IIF, polypeptide 1, 74kDa; Gtf2f1; MGC94148; OTTHUMP00000237859; RAP74; T2FA_HUMAN; TF2F1; TFIIF; TFIIF-alpha; Transcription initiation factor IIF subunit alpha; Transcription initiation factor RAP74;
100 μL
-20° C, Avoid Freeze/Thaw Cycles
2962, 476731, 699221
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Full length human recombit protein of GTF2F1 produced in HEK293T cell
Affinity Chromatography
Canine, Human, Non-human primate
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