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  6. GYKI 53655 hydrochloride, Tocris Bioscience™

GYKI 53655 hydrochloride, Tocris Bioscience™

Catalog Number 255550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
143692-48-2
C19H21ClN4O3
388.852
ASLCSBBDVWPSQT-UHFFFAOYSA-N
126757
5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide;hydrochloride
CC1CC2=CC3=C(C=C2C(=NN1C(=O)NC)C4=CC=C(C=C4)N)OCO3.Cl
This item is not returnable. View return policy
143692-48-2
C19H21ClN4O3
388.852
ASLCSBBDVWPSQT-UHFFFAOYSA-N
126757
5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide;hydrochloride
CC1CC2=CC3=C(C=C2C(=NN1C(=O)NC)C4=CC=C(C=C4)N)OCO3.Cl

Description

Non-competitive non-NMDA iGluR antagonist

Non-competitive AMPA and kainate receptor antagonist. Analog of GYKI 52466 (Cat. No. 1454). Prolongs the survival time after MgCl2- induced global cerebral ischemia. Exhibits anticonvulsant activity. Also blocks GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations.
Quantity 50 mg
Synonym gyki 53655 hydrochloride, gyki53655 hydrochloride, 7h-1,3-dioxolo 4,5-h 2,3 benzodiazepine-7-carboxamide, 8,9-dihydro-5-4-aminophenyl-n,8-dimethyl-, monohydrochloride, 1-4-aminophenyl-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5h-2,3-benzodiazepine hydrochloride, 5-4-aminophenyl-n,8-dimethyl-8,9-dihydro-7h-1,3 dioxolo 4',5':4,5 benzo 1,2-d 1,2 diazepine-7-carboxamide hydrochloride
Formula Weight 388.85
Percent Purity >99%
Chemical Name or Material GYKI 53655 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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