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H-2Ld/H-2Db Mouse, anti-Mouse, R718, Clone: 28-14-8, BD OptiBuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 751951

Catalog No. BDB751951


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Description

Description

The 28-14-8 antibody reacts with the α3 domain of the H-2D[b] MHC class I alloantigen. The antibody binds to H-2D[b] in the presence or absence of the β2 microglobulin chain. It cross-reacts with the α3 domain of H-2L[d], but not with K[d] or D[d], and with H-2D[q] and/or L[q]. Reactivity with haplotypes k, f, p, r, and s has not been observed. mAb 28-14-8 has been shown to block H-2L[d]- specific and H- 2L[d]-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes (CTL), but it does not block recognition of H-2L[d] positive target cells by Ly-6G2-positive NK cells.

Specifications

Specifications

H-2Ld/H-2Db
28-14-8
Liquid
50 μg
Refrigerate Upon Arrival
Monoclonal
Flow Cytometry
R718
Mouse
RUO
Primary
Mouse
SDS
Documents
Product Certifications
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