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Tocris Bioscience™ H-7 dihydrochloride

Protein kinase inhibitor

Supplier:  Tocris Bioscience™ 0542/50

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Catalog No. 05-425-0


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Description

Description

H-7 dihydrochloride is a protein kinase inhibitor (IC50 values for inhibition of PKA, PKG, PKC and myosin light chain kinase are 3.0, 5.8, 6.0 and 97.0 μM, respectively. H-7 shows antiviral activity against influenza A (IC50 = 10 μM) in vitro. H-7 also inhibits interleukin-stimulated secretion of IgM and blocks PMA -stimulated interleukin 1β production.
Specifications

Specifications

'±-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
>99%
Soluble to 20mM in DMSO
Observed MW: 364.29
108930-17-2
50 mg
C14H17N3O2S.2HCl
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Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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