H2AFX Mouse anti-Human, Clone: 980CT1.5.5, Abnova™
Mouse monoclonal antibody raised against synthetic peptide of human H2AFX.
Manufacturer: Abnova Corporation MAB12334
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
|Mouse monoclonal antibody raised against synthetic peptide of human H2AFX.|
|In PBS (0.09% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (1:25) Western Blot (1:1000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide (conjugated with KLH) corresponding to amino acids 1-30 at N-terminus region of human H2AFX.|
|Protein G purification|
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