H2AFY2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 170301AP150UL

Catalog No. 50-173-1337

Description

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Specifications

• Antigen: H2AFY2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2AFY2
• Gene Alias: Core histone macro H2A.2, H2A histone family, member Y2, H2AFY2, Histone macroH2A2, macroH2A2, mH2A2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361844, 404634, 55506
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8CCK0, Q9P0M6
• Gene Symbols: H2afy2
• Immunogen: H2AFY2 Fusion Protein Ag10487
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG