Invitrogen™ Hair Cortex Cytokeratin Monoclonal Antibody (AE13)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA15765

Catalog No. 01-674-884

Description

MA1-5765 detects Cytokeratin, AE13 in human and mouse samples. MA1-5765 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunohistochemistry procedures. The MA1-5765 immunogen is human hair keratins. This antibody reacts with acidic 44-46 kDa hair cortex keratins.

Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).

Specifications

• Antigen: Hair Cortex Cytokeratin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Gene Accession No.: Q6A162, Q6IFX3
• Gene Symbols: KRT40
• Immunogen: Human hair keratins from P3X63Ag. 8.653 cells.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: AE13
• Conjugate: Unconjugated
• Gene: KRT40
• Gene Alias: CK-40; Cytokeratin-40; K40; KA36; keratin 40; keratin 40, type I; keratin, type I cytoskeletal 40; Keratin-40; Krt40; ortholog of type I hair keratin KA36; type I hair keratin KA36
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 125115, 406221
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid