CD49a Hamster anti-Mouse, Brilliant Violet 421, Clone: Ha31/8, BD Optibuild™

Hamster Monoclonal Antibody

Supplier:  BD Biosciences 740046

Catalog No. BDB740046

Description

The Ha31/8 monoclonal antibody specifically binds to the 180-kDa integrin α 1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β 1 subunit (CD29) to form the α 1β 1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.

Specifications

• Antigen: CD49a
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Itga1; Integrin alpha-1; Integrin α1; Laminin and collagen receptor; VLA-1a
• Host Species: Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2 λ1

• Applications: Flow Cytometry
• Clone: Ha31/8
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Rat Emulsified Lewis Rat Glomeruli Cells
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only