CD49a Hamster anti-Mouse, Brilliant Violet 421, Clone: Ha31/8, BD Optibuild™
Hamster Monoclonal Antibody
Manufacturer: BD Biosciences 740046
The Ha31/8 monoclonal antibody specifically binds to the 180-kDa integrin α 1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β 1 subunit (CD29) to form the α 1β 1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.
|Brilliant Violet 421|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Itga1; Integrin alpha-1; Integrin α1; Laminin and collagen receptor; VLA-1a|
|Rat Emulsified Lewis Rat Glomeruli Cells|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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