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HBA1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 199901AP150UL
Description
This antibody detects a major band around 14-16 kDa in the western blot analysis of heart tissue and K-562 cells. A higher band around 26-27 kDa can also be observed occasionally, which may represents the dimer form of HBA1. The antibody is specific to HB
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5′- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3′. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5′ untranslated regions and the introns, but they differ significantly over the 3′ untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.Specifications
HBA1 | |
Polyclonal | |
Unconjugated | |
HBA1 | |
Alpha globin, HBA1, HBA2, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin, alpha 1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
3039 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Western Blot | |
0.24 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P69905 | |
HBA1 | |
Peptide | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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