HBG2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA5107140
Sequence homology: Cow: 100%; Dog: 77%; Goat: 100%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 93%; Rabbit: 75%; Rat: 83%; Sheep: 100%The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predomit at birth. The order of the genes in the beta-globin cluster is: 5 ft.- epsilon -- gamma-G -- gamma-A -- delta -- beta--3 ft..
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|PBS with 2% sucrose and 0.09% sodium azide; pH 7.4|
|Synthetic peptide located within the following region: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK|