HDAC10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549744
The antibody detects endogenous levels of total HDAC10 protein.A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized.
|Synthesized peptide derived from human HDAC10.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|Q969S8, Q6P3E7, Q569C4|
|Histone deacetylase 10, HD10|
|170787, 362981, 83933|
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