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HDAC10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549744

Catalog No. PA549744


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Description

Description

The antibody detects endogenous levels of total HDAC10 protein.

A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized.
Specifications

Specifications

HDAC10
Polyclonal
Unconjugated
HDAC10
Liquid
HDAC10
Synthesized peptide derived from human HDAC10.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q969S8, Q6P3E7, Q569C4
Histone deacetylase 10, HD10
Rabbit
IgG
100 μL
-20°C
Primary
170787, 362981, 83933
Documents
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