HDAC10 Mouse anti-Human, Clone: OTI7C3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525011
DescriptionA novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RP3-402G11.7, DKFZp761B039, MGC149722|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of HDAC10 produced in HEK293T cell|
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