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HDAC2 Rabbit anti-Canine, Hamster, Human, Mouse, Non-human primate, Rat, Alexa Fluor® 555, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1861A555

Catalog No. PIPA1861AZ


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Description

Description

PA1861A555 detects histone deacetylase 2 (HDAC2) from canine, hamster, human, mouse, non-human primate, rat tissues and cells. The PA1861A555 immunogen is a synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2. This immunizing peptide (Cat. No. PEP-070) is available for use in neutralization and control experiments.

Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Specifications

Specifications

HDAC2
Polyclonal
Alexa Fluor™ 555
HDAC2
Liquid
HDAC2
Synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Canine, Hamster, Human, Mouse, Non-human primate, Rat
Immunofluorescence
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Q92769, P70288
mRPD3, HD2, D10Wsu179e, YAF1, Yy1bp, RPD3
Rabbit
IgG
50 μL
4° C, store in dark, DO NOT FREEZE!
Primary
100764557, 15182, 3066, 475035, 84577
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