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HDAC4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 161651AP

Catalog No. 50-173-0764


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Description

Description

This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human HDAC4.

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
Specifications

Specifications

HDAC4
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P56524, Q6NZM9, Q99P99
HA6116, HD4, HDAC A, HDAC4, HDACA, histone deacetylase 4, KIAA0288
Rabbit
IgG
150 μL
-20°C
Primary
208727, 363287, 9759
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
HDAC4
Liquid
Hdac4
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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