DescriptionThis gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal domit polycystic kidney disease.
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Human, Mouse, Rat|
|15201, 294071, 3070|
|HELLS Fusion Protein Ag2558|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|helicase, lymphoid, HELLS, LSH, Lymphoid specific helicase, Nbla10143, PASG, SMARCA6|
|Antigen Affinity Chromatography|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok