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Thermo Scientific™ Lab Vision™ Heparan Sulfate Proteoglycan/Perlecan Ab-1, Rat Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.

Specifications

Antigen Heparan Sulfate Proteoglycan/Perlecan Ab-1
Clone A7L6
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Format Concentrated
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Products 2
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
RT794P0
View Documents
Thermo Scientific™
RT794P0
200µg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
RT794P1
View Documents
Thermo Scientific™
RT794P1
200µg/mL Unconjugated 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Heparan Sulfate Proteoglycan/Perlecan Ab-1, Rat Monoclonal Antibody.

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

Host Species: Rat

Clone: A7L6

Isotype: IgG2a/κ

Species Reactivity: Human, Cow, Pig, Mouse. Others not known.

Epitope: Not determined

Immunogen: Murine EHS laminin preparation

Molecular Weight: High

Positive Control: Tonsil

Cellular Localization: Basement membrane

Recommended for:

  • Immunohistochemistry (Frozen and acid-alcohol-fixed, paraffin-embedded)
  • Western Blotting (Not verified)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Heparan Sulfate Proteoglycan/Perlecan Ab-1
Immunohistochemistry (Frozen)
Concentrated
RUO
Primary
IgG2a kappa
A7L6
Monoclonal
Rat
Angiogenesis
Murine EHS laminin preparation
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