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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

$171.10 - $964.50

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Clone N12
Applications Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Format Concentrated
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Products 8
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS301B
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Thermo Scientific™
MS301B
200μg/mL Biotin 1mL Each for $964.50
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MS301B0
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Thermo Scientific™
MS301B0
200μg/mL Biotin 100μL Each for $234.50
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MS301B1
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Thermo Scientific™
MS301B1
200μg/mL Biotin 500μL Each for $635.00
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MS301P
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Thermo Scientific™
MS301P
200μg/mL Unconjugated 1mL Each for $757.50
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MS301P0
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Thermo Scientific™
MS301P0
200μg/mL Unconjugated 100μL Each for $171.10
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MS301P1
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Thermo Scientific™
MS301P1
200μg/mL Unconjugated 500μL Each for $483.00
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MS301P1ABX
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Thermo Scientific™
MS301P1ABX
1mg/mL Unconjugated 100μL Each for $527.50
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MS301PABX
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Thermo Scientific™
MS301PABX
1mg/mL Unconjugated 200μL Each for $806.50
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Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (~90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

HER-2/c-erbB-2/neu Ab-4
Immunofluorescence, Immunohistochemistry (Frozen)
Concentrated
RUO
Primary
IgG1
N12
Monoclonal
Murine
EGFR Family
Intact SKBR-3 breast cancer cells
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