HER-2 (Trastuzumab) Recombinant Human Monoclonal Antibody (4D5-8), Functional Grade, Fc Muted™, Leinco Technologies™

Human Recombinant Monoclonal Antibody

Supplier:  Leinco Technologies Inc LT1505500UG

Catalog No. 50-254-4127

Description

Specificity: This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Trastuzumab. Clone 4D5-8 recognizes human erbB-2. Endotoxin Level: <1.0 EU/mg as determined by the LAL method. Purity: ≥95% monomer by analytical SEC. Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco recombinant biosimilar antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. Storage: Functional grade biosimilar antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.

HER-2 (Trastuzumab) Recombinant Monoclonal antibody specifically detects HER-2 (Trastuzumab) in Human samples. It is validated for ELISA, Flow Cytometry, Immunohistochemistry, Mass Spectrometry

Specifications

• Antigen: HER-2 (Trastuzumab)
• Classification: Recombinant Monoclonal
• Concentration: ≥5.0 mg/mL
• Formulation: PBS with no preservative; pH 7.2-7.4
• Host Species: Human
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Mass Spectrometry
• Clone: 4D5-8
• Conjugate: Functional Grade
• Gene Alias: Herceptin; Metastatic lymph node gene 19
• Immunogen: Human epidermoid carcinoma cells (A431) over-expressing EGFR
• Quantity: 500 μg
• Primary or Secondary: Primary
• Content And Storage: 4°C short term, -80°C long term
• Form: Liquid