HER-3/c-erbB-3 Ab-4 Mouse Monoclonal Antibody, Epredia™

Epredia™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS262P1

Catalog No. MS262P1

Description

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Host Species: Mouse

Clone: H3.90.6; same as Ab90

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular fragment of recombinant human HER-3/c-erbB-3 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D cells

Cellular Localization: Cytoplasmic and membrane

Recommended for:

• Western Blotting (Not suitable)
• Immunofluorescence
• Immunoprecipitation
• Flow Cytometry
• Effect on Heregulin (NDF) Binding (Noninhibitory)
• Effect on Tumor Growth (Noninhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: HER-3/c-erbB-3 Ab-4
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Oncogenesis
• Target Species: Human
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunofluorescence, Immunoprecipitation
• Clone: H3.90.6; same as Ab90
• Conjugate: Unconjugated
• Immunogen: Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated