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HEXA Mouse anti-Human, Clone:3F10, Abnova™

Mouse monoclonal antibody raised against recombinant human HEXA.

Manufacturer:  Abnova Corporation MAB17715

Catalog No. 89-334-570


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Description

Description

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq]
Specifications

Specifications

HEXA
3F10
hexosaminidase A (alpha polypeptide)
In PBS (0.05% sodium azide)
Liquid
Mouse
IgG2b
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA, Western Blot
Unconjugated
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunocytochemistry
Immunohistochemistry
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.
HEXA
MGC99608, TSD
Recombinant protein corresponding to human HEXA from E. coli.
100μg
Antibody
3073
SDS
Documents
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