Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

HGF Mouse anti-Human, Mouse, Clone: 7-2, Abnova™

Mouse monoclonal antibody raised against human HGF.

Manufacturer:  Abnova Corporation MAB12568

Catalog No. 89-934-240


Add to cart

Description

Description

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

Specifications

HGF
7-2
Mouse monoclonal antibody raised against human HGF.
In PBS (0.01% sodium azide).
F-TCF/HGFB/HPTA/SF
Mouse
IgG2a, kappa
50 ug
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human, Murine
Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
HGF
Human HGF
Protein G purification
RUO
Primary
3082
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit