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HGK Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549780

Catalog No. PA549780


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Description

Description

The antibody detects endogenous levels of total HGK / MAP4K4 protein.

M4K4, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predomit in the liver, skeletal muscle and placenta.
Specifications

Specifications

HGK
Polyclonal
Unconjugated
MAP4K4
Liquid
MAP4K4
Synthesized peptide derived from internal of human MEKKK 4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O95819, P97820
HGK, KIAA0687, NIK
Rabbit
IgG
100 μL
-20°C
Primary
26921, 9448
Documents
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