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HI TOPK 032, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
487020-03-1
C20H11N5OS
369.402
BCSBXWKRZUPFHW-UHFFFAOYSA-N
hi topk 032,hi-topk-32,hi-topk-032,n-12-cyanoindolizino 2,3-b quinoxalin-2-yl thiophene-2-carboxamide,n-12-cyano-2-indolizino 2,3-b quinoxalinyl-2-thiophenecarboxamide,hi-topc-032,n-12-cyanindolizino 2,3-b quinoxalin-2-yl-2-thiophenecarboxamide,n-12-cyanoindolizino 2,3-b quinoxalin-2-yl-2-thiophenecarboxamide
1936439
N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)thiophene-2-carboxamide
C1=CC=C2C(=C1)N=C3C(=C4C=C(C=CN4C3=N2)NC(=O)C5=CC=CS5)C#N
This item is not returnable. View return policy
487020-03-1
C20H11N5OS
369.402
BCSBXWKRZUPFHW-UHFFFAOYSA-N
hi topk 032,hi-topk-32,hi-topk-032,n-12-cyanoindolizino 2,3-b quinoxalin-2-yl thiophene-2-carboxamide,n-12-cyano-2-indolizino 2,3-b quinoxalinyl-2-thiophenecarboxamide,hi-topc-032,n-12-cyanindolizino 2,3-b quinoxalin-2-yl-2-thiophenecarboxamide,n-12-cyanoindolizino 2,3-b quinoxalin-2-yl-2-thiophenecarboxamide
1936439
N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)thiophene-2-carboxamide
C1=CC=C2C(=C1)N=C3C(=C4C=C(C=CN4C3=N2)NC(=O)C5=CC=CS5)C#N

Selective T-LAK-cell-originated protein kinase (TOPK) inhibitor

T-LAK-cell-originated protein kinase (TOPK) inhibitor; exhibits selectivity for TOPK over other MAPKK family members including ERK1, JNK1 and p38. Blocks proliferation of HCT116 colon cancer cells; suppresses tumor growth in a colon cancer xenograft model. Also inhibits Chk1 (IC50 = 9.6 μM).

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Quantity 10mg
Formula Weight 369.4
Percent Purity >98%
Chemical Name or Material HI TOPK 032

Recommended Storage : Store at +4°C