Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Lab Vision™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody

Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Specifications

Antigen HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-4
Clone H1alpha67
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
View More Specs

Products 3
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS1164P0
View Documents
Thermo Scientific™
MS1164P0
200μg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1164P1ABX
View Documents
Thermo Scientific™
MS1164P1ABX
1mg/mL 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1164PABX
View Documents
Thermo Scientific™
MS1164PABX
1mg/mL 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

HIF-1 (hypoxia-inducible factor-1) is a heterodimer consisting of an alpha and a β subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. HIF-1 is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. HIF-1 activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth (VEGF), heme oxygenase-1, inducible nitric oxide synthase, and the glycolytic enzymes aldolase A, enolase 1, lactate dehydrogenase A, phosphofructokinase I, and phosphoglycerate kinase 1. The C-terminal of HIF-1 alpha binds to p300. p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF.

Host Species: Mouse

Clone: H1α67

Isotype: IgG2b/κ

Species Reactivity: Human, Sheep, Mouse, Rat and Ferret. Others not known.

Epitope: aa 432-528

Immunogen: Recombinant hHIF-1α (aa 432-528) protein

Molecular Weight: 120kDa

Positive Control: Mammalian cells cultured under reduced O2 tension

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Immunoprecipitation (Not verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-4
Immunohistochemistry (Paraffin)
Unconjugated
Murine
Transcription Regulation
Recombinant hHIF-1alpha (aa 432-528) protein
H1alpha67
Monoclonal
Concentrated
RUO
Primary
IgG2b kappa
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit